diphenhydramine-hcl manufacturer

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Description :
Diphenhydramine is a first-generation antihistamine possessing anticholinergic,antitussive, antiemetic, and sedative properties which is mainly used to treat allergies. Like most other first-generation antihistamines, the drug also has a powerful hypnotic effect, and for this reason is often used as a non-prescription sleep aid; especially in the form of diphenhydramine citrate. It may also be used for the treatment of extrapyramidal side-effects of many antipsychotics, such as the tremors that haloperidol can cause. In addition, injectable diphenhydramine can be used for life-threatening reactions (anaphylaxis) to allergens such as bee stings, peanuts, or latex, rather than risking the side-effects of epinephrine. It is a member of theethanolamine class of antihistaminergic agents. Diphenhydramine is a first generation antihistamine used to treat a number of conditions including allergic symptoms and itchiness, the common cold, insomnia, motion sickness, and extrapyramidal symptoms. Diphenhydramine is also used to treat Parkinson's disease by antagonizing acetylcholine in the muscarinic receptors; thus correcting the neurotransmitter imbalance of dopamine that also controls motor function in the brain; similar to other antimuscarinic agents such as atropine. As diphenhydramine is extensively metabolized by the liver, caution should be exercised when giving the drug to individuals with hepatic impairment.

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