aminophylline manufacturer

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Chemical Formula :
1,3-dimethyl-7H-purine-2,6-dione; ethane-1,2-diamine
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Description :
Aminophylline is a bronchodilator. It is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate. Aminophylline is a nonselective adenosine receptor antagonist and phosphodiesterase inhibitor capable of reversing ischemia-induced bradyasystole.It does this by improving the rate of return of spontaneous circulation (ROSC). After exhaustive conventional therapy, aminophylline is administered early in resuscitation efforts to re-establish cardiac rhythm. With aminophylline administration, the patient may have immediate resumption of cardiac electrical activity. Aminophylline should be an intervention with the ACLS treatment of atropine-resistant asystolic out-of-hospital cardiac arrest.

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